Assessment of methodological quality in DTA reviews

Description

This is a recorded video slidecast presentation by Lotty Hoof, deputy director of Cochrane Netherlands, delivered at a two-day workshop hosted by Cochrane Netherlands.

Methodological quality in the context of diagnostic test accuracy (DTA) reviews refers both to risk of bias and applicability of included studies. This presentation explains why and how to assess the quality of DTA studies. Key features of DTA study design are described, with examples to illustrate different sources of risk of bias. Finally, QUADAS-2 tool for assessing the methodological quality of DTA studies is presented.

Please note you will need to have Microsoft Silverlight installed in order to play the presentations. 

After using this resource, you should be able to...
  • Understand why it is important to assess methodological quality in a DTA review
  • Recognize sources of risk of bias in DTA studies
  • Use QUADAS-2 tool to assess methodological quality in a DTA review.
  • Present and investigate the results of the quality assessment in your DTA review

Assessment of methodological quality in DTA reviews

Author information: 
Hooft, Lotty
Acknowledgements: 

Thanks to Penny Whiting and Cochrane Netherlands.