Systematic reviews of preclinical animal research: current state of affairs

This is a recording of the Cochrane Canada Webinar on systematic reviews of preclinical animal studies, with Dr. Marlies Leenaars, SYRCLE  (SYstematic Review Centre for Laboratory animal Experimentation), Radboud University Medical Center, Nijmegen, The Netherlands.

The potential benefits of systematic reviews of preclinical animal studies encompass stimulating better science and improving judgements on possible translation to clinical trials.  The number of conducted systematic reviews of preclinical animal studies as well as the attention for this topic is growing. The webinar provides an overview of activities within laboratory animal science, the current state of affairs and what is needed for further progress.

After using this resource, you should be able to...
  • Outline the rationale behind the systematic reviews of preclinical animal studies
  • Discuss the challenges in conducting the systematic reviews of preclinical animal studies
  • Appreciate how attention to systematic reviews of preclinical animal studies has been growing in recent years
  • Identify tools and guidelines for systematic reviews of preclinical animal studies

Author information: 
Leenaars, Marlies
Acknowledgements: 

Cochrane Canada webinar series was produced with the support of Canadian Institutes of Health Research and Institute of Gender and Health, Institute of Health Services and Policy Research, Institute of Human Development, Child and Youth Health, Institute of Infection and Immunity, Institute of Musculoskeletal Health and Arthritis, and Institute of Nutrition, Metabolism and Diabetes. Blackboard Collaborate tool for producing webinars was provided by Pan American Health Organization (PAHO) / WHO Research Promotion and Development. Introduction by Adrianne Stevens.