Agenda:
There are many methods available to fit random-effects meta-analysis. However, until 2024, the only option available in RevMan has been the DerSimonian and Laird random-effects method. This method is known to have poor statistical performance in meta-analyses with characteristics commonly found in Cochrane reviews (e.g., meta-analyses with few studies). To address this issue, Cochrane is implementing new random-effects methods in RevMan. These include a new method for estimating the between-study (heterogeneity) variance, calculating the confidence interval for the summary effect, and adding prediction intervals to aid in interpreting random-effects meta-analysis findings. In two web clinics, we will provide participants with knowledge about these new methods and their implementation in RevMan. Specifically, in the first web clinic, we will outline the new methods, while in the second clinic, we will demonstrate the new methods using RevMan.