GRADE Handbook

The GRADE handbook describes the process of rating the quality of the best available evidence and developing health care recommendations following the approach proposed by the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) Working Group 

This is the most comprehensive resource on the GRADE approach and deals with both the use of GRADE in systematic reviews and its application in the guideline development process. The latest update of the Handbook was in in October 2013.

Author information: 
Schünemann, Holger; Brożek, Jan; Guyatt, Gordon; Oxman, Andrew
Acknowledgements: 

Grading of Recommendations, Assessment, Development and Evaluation (GRADE) Working Group