JCE series

JCE series: GRADE guidelines
JCE series: GRADE guidelines

GRADE Working Group has produced a series of guidance articles for systematic review and health technology assessment authors, guideline panelists and methodologists on how to apply the GRADE methodology framework. The series has been published in the Journal of Clinical Epidemiology (JCE) and the links to the articles are available below. Other GRADE-related publications are listed here.

Note that since the initial publications in this series, the term 'quality of evidence' has been replaced by 'certainty of evidence'.


Introductory articles


Rating the certainty of evidence


Summarizing the evidence


Making recommendations


Risk of bias


Values and preferences


Diagnostic tests


Network meta-analysis

GRADE guidelines: 23. Going from evidence to recommendations: considering resource use and modelling evidence for cost-effectiveness (under revision)
GRADE guidelines: 24. Strategies to optimize use of randomized and non-randomized studies in evidence syntheses that use GRADE (under revision)